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Rat IL-6 ELISA Kit, EZRIL6
Description:
Rat IL-6 ELISA Kit, EZRIL6
Qty/Pk:
96-well strip plate
Background Information:
Interleukin 6 (IL-6) is a prototypic member of the IL-6 superfamily of cytokines. It is secreted by a variety of lymphoid and non-lymphoid cells including: T cells, B cells, monocytes, fibroblasts, hepatocytes, endothelial cells and keratinocytes. Mature rat IL-6 is a 187 amino acid residue protein. At the protein sequence level, there is 39% identity between rat and human, and 87% identity between rat and mouse. The production of IL-6 can be induced by numerous signals, such as mitogenic or antigenic stimulation, lipopolysaccharides, calcium ionophores, cytokines and viruses.
As a pleiotropic cytokine, IL-6 plays important roles in immune response, inflammation, hematopoiesis, bone metabolism, nerve cell functions and cancer progression. Elevated serum IL-6 levels have been observed in a number of pathological conditions, including bacterial and viral infections, trauma, autoimmune diseases, inflammation and malignancies.
The Rat IL-6 ELISA Kit is a sandwich Enzyme-Linked Immunosorbent Assay (ELISA) with a 96-well strip plate that is pre-coated with a capture antibody. This kit is specifically designed for the accurate quantification of rat IL-6 from cell culture supernatant, serum, plasma and other biological fluids. It is analytically validated with ready-to-use reagents.
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Applications:
The Rat IL-6 ELISA Kit is a sandwich Enzyme-Linked Immunosorbent Assay (ELISA) is designed for the accurate quantification of rat IL-6 from cell culture supernatant, serum, plasma & other biological fluids.
Key Applications:
ELISA
Species Reactivity:
Rat
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Linearity of Dilution:
Contact Technical Service for this information
Sensitivity:
5.3 pg/mL
Product Name:
Rat IL-6 ELISA Kit, EZRIL6
Specificity:
4.1% cross-reactivity was observed for mouse IL-6. No other cross-reactivity was observed when this kit was used to analyze the following recombinant cytokines/chemokines, each at a concentration of 50 ng/mL.
Human: IL-6
Rat: IL-1a, IL-1b, IL-2, IL-4, IL-5, IL-10, IL-12, IL-13, IL-17A, IL-17F, IL-18, IL-22, IL-23, IL-33, CCL20, GM-CSF, IFN-g, KC, MCP-1, RANTES, TNF-a
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Analytes Available:
IL-6
Precision, %:
Intra-assay: <10 %
Inter-assay: <15 %
Accuracy:
96% |