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Rat IL-17A ELISA Kit, EZRIL17A
Description:
Rat IL-17A ELISA Kit, EZRIL17A
Qty/Pk:
96-well strip plate
Background Information:
Rat IL-17A (other synonyms include IL-17, Cytotoxic T Lymphocyte-Associated Antigen-8 [CTLA-8]) is a founding member of the IL-17 family of cytokines. IL-17 is mainly produced by Th17 cells, a small subset of T helper cells. IL-17 exhibits multiple biological activities including the induction of various proinflammatory cytokines and chemokines such as IL-6, IL-8, G-CSF, GM-CSF, GRO-α, and MCP-1 on a variety of cell types. IL-17 is also involved in the activation of NF-kB and costimulation of T cell proliferation. As a result of these roles, IL-17 has been linked to many immune and autoimmune-related diseases including rheumatoid arthritis, asthma, lupus and multiple sclerosis.
The ELISA kit is a Sandwich Enzyme-Linked Immunosorbent Assay (ELISA) with 96-well strip-plates that are pre-coated with a capture antibody.
The ELISA kits with pre-coated plates are specifically designed for the accurate quantification of analytes from cell culture supernatant, serum, plasma or other body fluids. All kits are analytically validated and provide ready-to-use reagents.
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Applications:
The Rat IL-17A ELISA kit is a S&wich Enzyme-Linked Immuno-sorbent Assay (ELISA) with 96 well strip plates that are pre-coated with a capture antibody.
Key Applications:
ELISA
Species Reactivity:
Rat
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Linearity of Dilution:
Contact Technical Service for this information
Sensitivity:
4 pg/mL
Product Name:
Rat IL-17A ELISA Kit, EZRIL17A
Specificity:
This kit cross-reacts with mouse IL-17A. Recombinant mouse IL-17A/F shows approximately 2.2% cross-reactivity in this assay.
No cross reactivity was observed when this kit was used to analyze the following recombinant cytokines/chemokines at up to 50 ng/mL.
Human: IL-1b, IL-2, IL-6, IL-8, IL-10, IL-11, IL-12 (p40), IL-13, IL-15, IL- 17A, IL-17A/F, IL-17E, IL-17F, IL-23, IL-27, IL-32, IFN-g, TSLP
Mouse: IL-2, IL-10, IL-12 (p70), IL-13, IL-17B, IL-17E, IL-17F, IL-22, IL- 33, FGF-basic, IFN-g, MCP-1, SCF, TNF-a
Rat: IL-1b, IL-2, IL-5, IL-6, IL-9, IL-10, IL-12 (p40), IL-13, IL-17E, IL-17F, IL-18, IL-22, IL-23, IL-33, CCL20, GM-CSF, IFN-g, KC, MCP-1, RANTES
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Analytes Available:
IL-17A
Precision, %:
Intra-assay: <10 %
Inter-assay: <15 %
Accuracy:
106% |