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Human Recombinant Cyclophilin G
An immunophilin family protein catalyzing the isomerization of peptide bonds
Product Overview
Product Name: Human Recombinant Cyclophilin G
Alternate Name/Synonyms: Peptidyl-prolyl cis-trans isomerase G, Peptidyl prolyl cis trans isomerase G, PPIase G, PPIase-G, Rotamase G, PPIG, Peptidylprolyl isomerase G, Peptidyl-prolyl isomerase G, Peptidyl prolyl isomerase G, Rotamase G, Rotamase-G, Clk-associating RS-cyclophilin, Clk associating RS cyclophilin, CARS-cyclophilin, CARS cyclophilin CARS-Cyp, CARS Cyp, SR-cyclophilin, SR cyclophilin, SR-cyp, SRcyp, SR cyp, CASP10, CASP-10, CASP 10, CYP, MGC133241
Gene Symbol: PPIG
Accession #: Q13427
Gene ID: 9360
Source: E. coli
Appearance: Liquid
Physical Form Description: 1 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT, and 10% glycerol.
Molecular Weight: 21.6 kDa
Purity by SDS-PAGE: ≥95%
Purity by HPLC: N/A
Endotoxin Level: N/A
Biological Activity: Specific activity is > 200 nmoles/min/mg.
Reconstitution Instructions: N/A
Storage Temp.: -80°C
Shipping: Gel pack
Background Information: Peptidyl-prolyl cis-trans isomerase G (PPIG), also known as Cyclophilin G, is a member of peptidylprolyl cis-trans isomerase family (PPIases). This protein catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and is implicated in the folding, transport, and assembly of proteins. It is localized to the nuclear speckles, a nuclear compartment rich in splicing factors, and interacts with the splicing factors SC35 and pinin. Cyclophilin G also may play an important role in the regulation of pre-mRNA splicing.
Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGIKVQRPRC FFDIAINNQP AGRVVFELFS DVCPKTCENF RCLCTGEKGT GKSTQKPLHY KSCLFHRVVK DFMVQGGDFS EGNGRGGESI YGGFFEDESF AVKHNKEFLL SMANRGKDTN GSQFFITTKP TPHLDGHHVV FGQVISGQEV VREIENQKTD AASKPFAEVR ILSCG
Handling: Centrifuge the vial prior to opening
USAGE: For Research Use Only! Not For Use in Humans. |