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Human Recombinant PPIL1
An immunophilin family protein catalyzing the isomerization of peptide bonds
Product Overview
Product Name: Human Recombinant PPIL1
Alternate Name/Synonyms: Peptidylprolyl isomerase (cyclophilin)-like 1, Rotamase, CGI-124, CYPL1, hCyPX, PPIase.
Gene Symbol: PPIL1
Accession #: Q9Y3C6
Gene ID: 51645
Source: E. coli
Appearance: Liquid
Physical Form Description: 1 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol.
Molecular Weight: 19.3 kDa
Purity by SDS-PAGE: ≥95%
Purity by HPLC: N/A
Endotoxin Level: N/A
Biological Activity: Specific activity is > 300 nmoles/min/mg.
Reconstitution Instructions: N/A
Storage Temp.: -80°C
Shipping: Gel pack
Background Information: Peptidylprolyl isomerase (cyclophilin)-like 1, also known as PPIL1, is a member of peptidyl-propyl cis trans isomerase (PPIase) family, which catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerates the folding of proteins. Human PPIL1 might play an important role in proliferation of cancer cells through modulation of phosphorylation of stathmin. So it can be developed as a novel molecular target for colon-cancer therapy.
Amino Acid Sequence: MAAIPPDSWQ PPNVYLETSM GIIVLELYWK HAPKTCKNFA ELARRGYYNG TKFHRIIKDF MIQGGDPTGT GRGGASIYGK QFEDELHPDL KFTGAGILAM ANAGPDTNGS QFFVTLAPTQ WLDGKHTIFG RVCQGIGMVN RVGMVETNSQ DRPVDDVKII KAYPSGLEHH HHHH
Handling: Centrifuge the vial prior to opening
USAGE: For Research Use Only! Not For Use in Humans. |