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Human Recombinant Cyclophilin F
An immunophilin family protein catalyzing the isomerization of peptide bonds
Product Overview
Product Name: Human Recombinant Cyclophilin F
Alternate Name/Synonyms: Human Recombinant Cyclophilin F, Peptidylprolyl isomerase F, PPIF, CYP3, Cyp-D.
Gene Symbol: PPIF
Accession #: P30405
Gene ID: 10105
Source: E. coli
Appearance: Liquid
Physical Form Description: 1 mg/ml solution in 20 mM Tris-HCl buffer (pH 7.5) containing 1 mM DTT 10% glycerol.
Molecular Weight: 21 kDa
Purity by SDS-PAGE: ≥95%
Purity by HPLC: N/A
Endotoxin Level: < 1.0 EU per 1 μg of protein
Biological Activity: Specific activity is > 250 nmoles/min/mg
Reconstitution Instructions: N/A
Storage Temp.: -80°C
Shipping: Gel pack
Background Information: Cyclophilin F is a member of peptidyl-prolyl cis-trans isomerase family. They are highly-conserved cytoplasmic enzymes that accelerate protein folding. It is a part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.
Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH PSFMCQAGDF TNHNGTGGKS IYGSRFPDEN FTLKHVGPGV LSMANAGPNT NGSQFFICTI KTDWLDGKHV VFGHVKEGMD VVKKIESFGS KSGRTSKKIV ITDCGQLS
Handling: Centrifuge the vial prior to opening
USAGE: For Research Use Only! Not For Use in Humans. |