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AhR Agonist V, VAF347

产品编号: 182690-10MG     查看说明书
产品名称: AhR Agonist V, VAF347  .0   订购此产品 
供应商: Merck
规格: ***
目录价: 1,837.00
库存状态: 3周到货
CAS编号:
应用范围: 生化实验
种属来源:
相关信息:

AhR Agonist V, VAF347
(4-(3-Chloro-phenyl)-pyrimidin-2-yl)-(4-trifluoromethyl-phenyl)-amine
A cell-permeable pyrimidinylphenylamine compound that directly and reversibly targets aryl hydrocarbon receptor (AhR) with high-affinity, and induces AhR signaling. Reported to act as an immunomodulator with anti-inflammatory properties. Potently suppresses IgE secretion in B-cells with an IC50 of ~2 nM, and inhibits dendritic cells-mediated T-cell proliferation and cytokine production. Further, decreases lung eosinophilia in B-cell-deficient mice, and allergic inflammation. Downregulates PU.1 transcription factor, and impairs human monocytes and Langerhans dendritic cells differentiation.
产品信息
Form  White solid
Molar mass  349.7
Protect from Light  是的
Packaged under inert gas  是的
Purity  ≥99% by HPLC
Solubility  DMSO
Chemical formula  C17H11ClF3N3
商店和运输信息
Storage  +2°C to +8°C
Ship  Ambient Temperature Only
Standard Handling

保存条件: 2°C - 8°C
说明书地址: 点击查看详细
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