Mitoxantrone A topoisomerase II inhibitor Product Overview Product Name: Mitoxantrone Alternate Name/Synonyms: 1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione Description: An anti-tumor antibiotic and type II topoisomerase inhibitor. It disrupts DNA synthesis and DNA repair in both healthy and cancer cells. Mitoxantrone also displays broad immunosuppressive activity inhibiting proliferation of all classes of lymphocytes and inducing apoptosis of antigen-presenting T cells. Peptide Sequence: N/A Appearance: Dark blue soild Formulation: N/A CAS Number: 65271-80-9 Molecular Formula: C₂₂H₂₈N₄O₆ Molecular Weight: 444.48 Purity: ≥98% Solubility:DMSO Storage Temp.: -20°C Shipping Conditions: gel pack Handling: Protect from air and light SMILES: C1=CC(=C2C(=C1NCCNCCO)C(=O)C3=C(C=CC(=C3C2=O)O)O)NCCNCCO InChi: InChI=1S/C22H28N4O6/c27-11-9-23-5-7-25-13-1-2-14(26-8-6-24-10-12-28)18-17(13)21(31)19-15(29)3-4-16(30)20(19)22(18)32/h1-4,23-30H,5-12H2 InChi Key: KKZJGLLVHKMTCM-UHFFFAOYSA-N PubChem CID: 4212 MDL Number: MFCD00242942 USAGE: For Research Use Only! Not For Use in Humans.
