7,3',4'-Trihydroxyisoflavone

7,3',4'-Trihydroxyisoflavone
An ATP-competitive inhibitor of Cot and MKK4
Product Overview
Product Name: 7,3',4'-Trihydroxyisoflavone
Alternate Name/Synonyms: 3-(3,4-Dihydroxyphenyl)-7-hydroxy-4H-chromen-4-one; 3’-Hydroxydiadzein; THIF; 7,3’,4’-THIF
Description: An ATP-competitive inhibitor of Cot and MKK4 that subsequently suppresses UVB-induced COX-2 expression in JB6 P+ mouse epidermal cells.
Peptide Sequence: N/A
Appearance: Off-white solid
Formulation: N/A
CAS Number: 485-63-2
Molecular Formula: C₁₅H₁₀O₅
Molecular Weight: 270.24
Purity: ≥98%
Solubility:DMSO
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: C1=CC(=C(C=C1C2=COC3=C(C2=O)C=CC(=C3)O)O)O
InChi: InChI=1S/C15H10O5/c16-9-2-3-10-14(6-9)20-7-11(15(10)19)8-1-4-12(17)13(18)5-8/h1-7,16-18H
InChi Key: DDKGKOOLFLYZDL-UHFFFAOYSA-N
PubChem CID: 5284648
MDL Number: MFCD00143002
USAGE: For Research Use Only! Not For Use in Humans.