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Mitoxantrone
A topoisomerase II inhibitor
Product Overview
Product Name: Mitoxantrone
Alternate Name/Synonyms: 1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione
Description: An anti-tumor antibiotic and type II topoisomerase inhibitor. It disrupts DNA synthesis and DNA repair in both healthy and cancer cells. Mitoxantrone also displays broad immunosuppressive activity inhibiting proliferation of all classes of lymphocytes and inducing apoptosis of antigen-presenting T cells.
Peptide Sequence: N/A
Appearance: Dark blue soild
Formulation: N/A
CAS Number: 65271-80-9
Molecular Formula: C₂₂H₂₈N₄O₆
Molecular Weight: 444.48
Purity: ≥98%
Solubility:DMSO
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: C1=CC(=C2C(=C1NCCNCCO)C(=O)C3=C(C=CC(=C3C2=O)O)O)NCCNCCO
InChi: InChI=1S/C22H28N4O6/c27-11-9-23-5-7-25-13-1-2-14(26-8-6-24-10-12-28)18-17(13)21(31)19-15(29)3-4-16(30)20(19)22(18)32/h1-4,23-30H,5-12H2
InChi Key: KKZJGLLVHKMTCM-UHFFFAOYSA-N
PubChem CID: 4212
MDL Number: MFCD00242942
USAGE: For Research Use Only! Not For Use in Humans. |