ODN 2006 Vaccigrade™
ODN 2006 (ODN 7909) is a synthetic oligodeoxynucleotide containing unmethylated CpG motifs (CpG ODNs). CpG ODNs are recognized by TLR9, which is expressed exclusively on human B cells and plasmocytoid dendritic cells (pDCs), thereby inducing Th1-dominated immune responses.
ODN 2006 VacciGrade™ is suitable for preclinical studies. It is prepared under strict aseptic conditions. It is guaranteed sterile and thoroughly tested for the presence of endotoxins.
ODN 2006 VacciGrade™ is for research use only, not for use in humans.
Synonyms: ODN 7909, PF_3512676
Specificity: Th1 response
Working concentration: 20 - 50 μg/mouse
Solubility: 2 mg/ml in physiological water
ODN 2006 sequence: 5’-tcgtcgttttgtcgttttgtcgtt-3’ (24 mer)
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