ODN 1826 VacciGrade

ODN 1826 VacciGrade™
ODN 1826 isa synthetic oligodeoxynucleotide containing unmethylated CpG motifs (CpG ODNs). CpG ODNs are recognized by TLR9, which is expressed exclusively on human B cells and plasmocytoid dendritic cells (pDCs), thereby inducing Th1-dominated immune responses.
ODN 1826 VacciGrade™ is suitable for preclinical studies. It is prepared under strict aseptic conditions. It is guaranteed sterile and thoroughly tested for the presence of endotoxins.
ODN 1826 VacciGrade™ is for research use only, not for use in humans.
Specificity: Th1 response
Working concentration: 20 - 50 μg/mouse
Endotoxin level: <1 EU/mg
Solubility: 2 mg/ml in physiological water
ODN1826 sequence: 5’-tccatgacgttcctgacgtt-3’ (20 mer)