AG 126 α-Cyano-(3-hydroxy-4-nitro)cinnamonitrile A cell-permeable inhibitor of lipopolysaccharide (LPS)-induced synthesis of tumor necrosis factor-α and nitric oxide in murine peritoneal macrophages. Blocks LPS-induced tyrosine phosphorylation of a p42MAPK/ERK2 protein substrate. Reduces the expression of iNOS and COX-2 in lungs of rats treated with carrageenan. Blocks glucocorticoid-induced COX-2 activity in human amnion cells (IC50 = 15.38 µM). 产品信息 Form Yellow solid Primary Target COX-2 activity Primary Target IC50 15.38 mM Molar mass 215.2 Protect from Light 是的 Purity ≥95% by HPLC Solubility DMF or DMSO Chemical formula C10H5N3O3 CAS number 118409-62-4 商店和运输信息 Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges. Storage -20°C Ship Ambient Temperature Only Toxic
