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Casein Kinase II Inhibitor V, Quinalizarin
A cell-permeable hydroxylated anthraquinone compound that acts as a potent (IC50 = 110 nM), highly selective (IC50 >1µM against CK1 and 83 other kinases), and ATP-competitive (Ki = 50 nM) CK2 inhibitor with greater selectivity than TBB (Cat. Nos. 218697 and 218708) and DMAT (Cat. Nos. 218699 and 218706) against DYRK1a, PIM1/3, and HIPK2. Quinalizarin is about 4.3- and 1.9-fold more effective than TBB, respectively, in cellular CK2 activity inhibition and in apoptosis induction in Jurkat cell cultures.
产品信息
Form Dark red solid
Molar mass 272.2
Protect from Light 是的
Packaged under inert gas 是的
Purity ≥95% by HPLC
Solubility DMSO
Chemical formula C14H8O6
CAS number 81-61-8
商店和运输信息
Storage +2°C to +8°C
Ship Ambient Temperature Only
Irritant
安全标示
S Phrase S: 26-36
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
R Phrase R: 36/37/38
Irritating to eyes, respiratory system and skin. |