CASEIN KINASE II INHIBITOR VI, TMCB

Casein Kinase II Inhibitor VI, TMCB
ERK8 Inhibitor I, 4,5,6,7-Tetrabromo-2-dimethylamino-1-carboxymethyl-benzimidazole, K66, Erk Inhibitor VI
A cell-permeable tertabromobenzimidazolo TBB (Cat. Nos. 218699 and 218708) analog that acts as a highly selective (IC50 >10 µM against 71 other kinases) ATP-competitive inhibitor against CK2 (IC50 = 500 nM; Ki = 250 nM) and ERK8 (IC50 = 500 nM). K66 is reported to be more selective than either TBB or DMAT and selective CK2 inhibition by K66 is shown to be cytotoxic to non-ERK8-expressing Jurkat cells.
产品信息
Form  White powder
Molar mass  534.8
Protect from Light  是的
Packaged under inert gas  是的
Purity  ≥97% by HPLC
Solubility  DMSO
Chemical formula  C11H9Br4N3O2
CAS number  905105-89-7
商店和运输信息
Storage  +2°C to +8°C
Ship  Ambient Temperature Only
Irritant
安全标示
S Phrase  S: 26-36
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
R Phrase  R: 36/37/38
Irritating to eyes, respiratory system and skin.