Dolastatin 15 Microtubule inhibitor Marine natural product from the sea hare Dolabella auricularia. Noncompetitively inhibits binding of vincristine to tubulin but has been shown to bind to the RZX/MAY region. Inhibits microtubule assembly and induces apoptosis and Bcl-2 phosphorylation in several malignant cell types. Product Specification MW: 837.1 CAS: 123884-00-4 Purity: ≥98% (HPLC Appearance: White solid. Long Term Storage: -20°C