Swinholide A Disrupts actin cytoskeleton Cytotoxic agent which disrupts actin cytoskeleton in cultured cells. Sequesters and stabilizes actin dimers in vivo with a 1:1 binding stoichiometry and rapidly severs actin filaments with high cooperativity. Product Specification Formula: C78H132O20 MW: 1389.9 Source: Isolated from marine sponge Theonella swinhoei. CAS: 95927-67-6 Formulation: Liquid. In DMSO. Purity: ≥98% (TLC) Solubility: Soluble in DMSO. Long Term Storage: -20°C Use/Stability: Stable for at least 1 year after receipt when stored, as supplied, at -20°C.
