|
Swinholide A
Disrupts actin cytoskeleton
Cytotoxic agent which disrupts actin cytoskeleton in cultured cells. Sequesters and stabilizes actin dimers in vivo with a 1:1 binding stoichiometry and rapidly severs actin filaments with high cooperativity.
Product Specification
Formula: C78H132O20
MW: 1389.9
Source: Isolated from marine sponge Theonella swinhoei.
CAS: 95927-67-6
Formulation: Liquid. In DMSO.
Purity: ≥98% (TLC)
Solubility: Soluble in DMSO.
Long Term Storage: -20°C
Use/Stability: Stable for at least 1 year after receipt when stored, as supplied, at -20°C. |