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Myostatin, human recombinant
A secreted growth differentiation factor
Product Overview
Alternate Names / Synonyms: human Myostatin, Myostatin, h-Myostatin, rh-Myostatin, recombinant human Myostatin, recombinant Myostatin
Gene Symbol: GDF8
Accession #: O14793
Gene ID: 2660
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Sterile filtered and lyophilized with no additives
Molecular Weight: 24.8 kDa
Purity by SDS-PAGE: ≥98%
Purity by HPLC: ≥98%
Endotoxin Level: <0.1 ng/μg
Biological Activity: Determined by its ability to inhibit the proliferation of MPC-11 cells. The ED₅₀ for this effect is <20 ng/ml.
Reconstitution Instructions: It is recommended to reconstitute the lyophilized human Myostatin in sterile 20 mM acetic acid to a concentration of 0.1 to 1.0 mg/ml. This solution can then be diluted into other aqueous buffers.
Storage Temp.: -20°C
Shipping: Gel pack
Background Information: Myostatin, also known as Growth Differentiation Factor-8 (GDF-8), belongs to the TGF-β superfamily. Along with other members of the TGF-β family, Myostatin plays a crucial role as a regulator for embryonic development and tissue homeostasis in adult animals. Early studies show that Myostatin has the ability to halt muscle growth. New research has further suggested that Myostatin may also be involved in reducing and preventing adiposity and type-2 diabetes. Human Myostatin is a homodimeric protein with each subunit containing 109 amino acid residues with a total molecular weight of 24.8 kDa.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans. |