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IL-22, murine recombinant
A potent mediator of cellular inflammatory responses
Product Overview
Alternate Names / Synonyms: murine IL-22, IL-22, IL22, IL 22, m-IL-22, rm-IL-22, recombinant murine IL-22, recombinant IL-22, IL, interluekin
Gene Symbol: IL22
Accession #: Q9JJY9
Gene ID: 50929
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Lyophilized from 1X PBS Solution
Molecular Weight: 33.4 kDa
Purity by SDS-PAGE: ≥97%
Purity by HPLC: ≥97%
Endotoxin Level: <0.1 ng/μg
Biological Activity: Recombinant murine IL-22 is fully biologically active when compared to a standard. The ED₅₀ as determined by its ability to induce IL-10 secretion in Colo205 cells is less than 0.5 ng/ml, corresponding to a specific activity of 2 x 10⁶ IU/mg.
Reconstitution Instructions: Reconstitute in water to a concentration of 0.1 to 1.0 mg/ml. This solution can then be stored at 4°C for 1 week or -20°C for future use. For long term storage, it is recommended to add a carrier protein (e.g., 0.1% BSA). Avoid repeating freeze/thaw cycles.
Storage Temp.: -20°C
Shipping: Gel pack
Background Information: Murine Interleukin-22 (IL-22), also known as T cell-derived inducible factor (ILTIF), is a cytokine that is structurally related to IL-10. Studies have shown that IL-22 induces acute-phase reactants in vitro and in vivo, suggesting that the cytokine contributes to the regulation of inflammatory responses. Recombinant murine IL-22 contains 2 x 146 amino acid chains having a total molecular mass of 33.4 kDa.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans. |