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TLR10 Native Genes
Toll-Like Receptor 10 native genes in expression plasmid
Alias: CD290
TLR10 is the last human member of the TLR family discovered so far, and its function and direct ligand are still unknown.
Its murine counterpart, if it exists, has not been identified yet.
hTLR10 is preferentially expressed on immune cells present in lymphoid tissues [1]. Phylogenetic analysis indicates that among all the hTLRs, hTLR10 is most closely related to hTLR1 and hTLR6; the overall amino acid identity is 50% and 49%, respectively.
These observations suggest that hTLR10 is involved in the immune response like other known TLRs and might act as a co-receptor similarly to TLR1 and TLR6.
This gene is available in pUNO1 expression plasmid selectable with Blasticidin or in pUNO3 expression plasmid selectable with Hygromycin or in pUNO1 expression plasmid selectable with Blasticidin.
Bovine TLR10 Native Genes (pUNO1-bTLR10)
Genbank: NM_001076918.1
ORF Size: 2439 bp
Subclone: AgeI - NheI
Human TLR10 (pUNO1-hTLR10)
ORF Size: 2436 bp
Subclone: AgeI - NheI
Human TLR10 (pUNO3-hTLR10)
ORF Size: 2436 bp
Subclone: AgeI - NheI
Pig TLR10 (pUNO1-pTLR10)
Genbank: AB210286.1
ORF Size: 2436 bp
Subclone: AgeI - NheI
Rat TLR10 (pUNO1-rTLR10)
ORF Size: 2436 bp
Subclone: BspHI - NheI
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