|
Bromodomain Testis-specific Protein (BrdT, domain 257-382 aa), human recombinant
A protein involved in chromatin targeting
Product Overview
Product Name: Bromodomain Testis-specific Protein (BrdT, domain 257-382 aa), human recombinant
Alternate Name/Synonyms: BrdT, Cancer/testis antigen 9, CT9, RING3-like protein
Gene Symbol: BRDT
Accession #: Q58F21
Gene ID: 676
Source: E. coli
Appearance: Liquid
Physical Form Description: rh-BrdT is supplied as a solution in 50 mM Tris, pH 8.0, 150 mM NaCl and 10% Glycerol.
Molecular Weight: 14.9 kDa (126 aa, 257-382 aa + NT His Tag)
Purity by SDS-PAGE: ≥98%
Purity by HPLC: N/A
Endotoxin Level: N/A
Biological Activity: N/A
Reconstitution Instructions: N/A
Storage Temp.: -80°C
Shipping: Dry ice
Background Information: BrdT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence. The bromodomain is found in proteins that regulate transcription. BrdT drives a meiotic and post-meiotic gene expression program. It also controls the genome-wide post-meiotic genome reorganization that occurs after histone hyperacetylation in elongating spermatids. It may play a role in the transcriptional regulation of spermatogenesis. It also seems to have a structural ATP-independent role in the reorganization of acetylated chromatin. BioVision’s recombinant protein includes Bromo 1 domain (257-382 aa) with N-terminal His-tag.
Amino Acid Sequence: N/A
Handling: Centrifuge the vial prior to opening
USAGE: For Research Use Only! Not For Use in Humans. |