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Description
A cytotoxic agent, which inhibits DNA topoisomerase I, induces strand breaks in chromosomal DNA and induces apoptosis.
Specifications
Cas No. 7689-03-4
Product ID C0150
Product Name Camptothecin
Chemical Name (S)-4-Ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino- [1,2-b]quinoline-3,14(4H,12H)-dione
Formula Wt. 348.35
Melting Point 264oC-267oC(dec.)
Purity ≥98%
Solubility Soluble in DMSO.
Store Temp -20oC
Ship Temp Ambient
References Hertzberg, R.P., Caranfa, M.J., Hecht, S.M. Biochemistry. 28:4629-4638 (1989). Cotter, T.G., Glynn, J.M., Echeverri, F., Green, D.R. Anticancer Res. 12:773-9 (1992). |