Tigecycline 9-t-Butylglycylamido-minocycline A broad-spectrum glyclcycline class of antimicrobial agent that is active against both Gram positive and Gram negative bacteria. Exhibits toxicity for human AML cells at all stages of development in both in vitro and in vivo models. Selectively kills leukemic stem and progenitor cells (LD50 ~10 µM) and reduces the repopulating ability of the primary AML cells while sparing normal hematopoietic cells. Its action on growth and viability of eukaryotic cells is shown to be due to its inhibitory effects on mitochondrial protein translation and respiratory complex activity. 产品信息 Form Orange powder Molar mass 585.7 Protect from Light 是的 Packaged under inert gas 是的 Purity ≥99% by HPLC Solubility DMSO Chemical formula C29H39N5O8 CAS number 220620-09-7 商店和运输信息 Storage +2°C to +8°C Ship Ambient Temperature Only Irritant