InSolution™ Cyclopamine, V. californicum A cell-permeable steroidal alkaloid and cholesterol mimic that displays both teratogenic and antitumor activities. It disrupts cholesterol bio-synthesis and specifically antagonizes shh (Sonic Hedgehog) signaling pathway through direct interaction with Smo (smoothened), a distant relative of G-protein-coupled receptors. A valuable tool for studying the involvement of shh signaling in the development of various tumors. Tomatidine (Cat. No. 614350) can be used as a negative control. The solid form of this compound (Cat. No. 239803) is also available. 产品信息 Form Liquid Formulation Supplied as a 10 mM (5 mg/1.22 mL) solution of Cyclopamine, V. californicum (Cat. No. 239803) in EtOH. Molar mass 411.6 Protect from Light 是的 Hygrocopic 是的 Avoid freeze/thaw 是的 Packaged under inert gas 是的 Purity ≥97% by NMR Chemical formula C27H41NO2 商店和运输信息 Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges. Storage ≤ -70°C Ship Dry Ice Only Flammable 安全标示 S Phrase S: 16-7 Keep away from sources of ignition - No Smoking. Keep container tightly closed. R Phrase R: 10 Flammable.