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Sirtinol
A selective sirtuin deacetylase inhibitor
Product Overview
Product Name: Sirtinol
Alternate Name/Synonyms: 2-[(2-Hydroxynaphthalen-1-ylmethylene)amino]-N-(1-phenethyl)benzamide; Sir Two Inhibitor Naphthol
Description: Cell-permeable. A selective sirtuin deacetylase inhibitor with IC50 values of 38, 68 and 131 μM for SIRT2, Sir2p and SIRT1 respectively. Sirtinol has no effect on HDAC1 activity. Sirtinol inhibits the growth of cancer cells and suppresses inflammatory signaling in human dermal microvascular endothelial cells.
Peptide Sequence: N/A
Appearance: Yellow solid
Formulation: N/A
CAS Number: 410536-97-9
Molecular Formula: C₂₆H₂₂N₂O₂
Molecular Weight: 394.47
Purity: ≥98%
Solubility:DMSO (100 mM)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: CC(C1=CC=CC=C1)NC(=O)C2=CC=CC=C2NC=C3C(=O)C=CC4=CC=CC=C43
InChi: InChI=1S/C26H22N2O2/c1-18(19-9-3-2-4-10-19)28-26(30)22-13-7-8-14-24(22)27-17-23-21-12-6-5-11-20(21)15-16-25(23)29/h2-18,27H,1H3,(H,28,30)/b23-17-
InChi Key: YUGODMKHHCZZOI-QJOMJCCJSA-N
PubChem CID: 5717148
MDL Number: MFCD00810186
USAGE: For Research Use Only! Not For Use in Humans. |