|
Myeloperoxidase Inhibitor
A potent myeloperoxidase (MPO) inhibitor
Product Overview
Product Name: Myeloperoxidase Inhibitor
Alternate Name/Synonyms: 4-Aminobenzoic hydrazide; MPO Inhibitor; 4-ABH
Description: A potent, irreversible, and specific inhibitor of the peroxidation activity of myeloperoxidase (MPO; IC₅₀ = 300 nM). Does not affect catalase or glutathione peroxidase activities. Also displays no effect on the production of superoxide by neutrophils. Shown to inhibit H₂O₂-induced apoptosis in HL-60, human leukemia cells.
Peptide Sequence: N/A
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 5351-17-7
Molecular Formula: C₇H9N₃O
Molecular Weight: 151.17
Purity: ≥95% by HPLC
Solubility:DMSO
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from light and mositure
SMILES: C1=CC(=CC=C1C(=O)NN)N
InChi: InChI=1S/C7H9N3O/c8-6-3-1-5(2-4-6)7(11)10-9/h1-4H,8-9H2,(H,10,11)
InChi Key: WPBZMCGPFHZRHJ-UHFFFAOYSA-N
PubChem CID: 21450
MDL Number: MFCD00007606
USAGE: For Research Use Only! Not For Use in Humans. |