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SANT-2
A potent Hedgehog (Hh) signaling pathway antagonist
Product Overview
Product Name: SANT-2
Alternate Name/Synonyms: N-[3-(1H-Benzimidazol-2-yl)-4-chlorophenyl]-3,4,5-triethoxybenzamide
Description: Cell-permeable. A potent antagonist of Hedgehog (Hh) signaling pathway. Antagonizes smoothened receptor activity (KD = 12 nM) and inhibits SAG (Cat. No. 1939-500,1000) activity. SANT-2 should be a useful tool to study the Hh signaling pathway.
Peptide Sequence: N/A
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 329196-48-7
Molecular Formula: C₂₆H₂₆ClN₃O₄
Molecular Weight: 479.96
Purity: ≥95% by NMR
Solubility:DMSO (100 mM) or EtOH (100 mM)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from light
SMILES: CCOC1=CC(=CC(=C1OCC)OCC)C(=O)NC2=CC(=C(C=C2)Cl)C3=NC4=CC=CC=C4N3
InChi: InChI=1S/C26H26ClN3O4/c1-4-32-22-13-16(14-23(33-5-2)24(22)34-6-3)26(31)28-17-11-12-19(27)18(15-17)25-29-20-9-7-8-10-21(20)30-25/h7-15H,4-6H2,1-3H3,(H,28,31)(H,29,30)
InChi Key: VQOJFGFKIVFMDH-UHFFFAOYSA-N
PubChem CID: 1367095
MDL Number: N/A
USAGE: For Research Use Only! Not For Use in Humans. |