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Elastase Inhibitor
A potent, irreversible human leukocyte elastase (HLE) inhibitor
Product Overview
Product Name: Elastase Inhibitor
Alternate Name/Synonyms: MeOSuc-Ala-Ala-Pro-Ala-chloromethylketone; MeOSuc-AAPA-CMK
Description: A potent, irreversible inhibitor of human neutrophil elastase (HNE). The structure of the enzyme-inhibitor complex reveals crosslinking of the catalytic residues His-57 and Ser-195 by the peptidyl chloromethylketone.
Peptide Sequence: Yes
Appearance: White solid
Formulation: N/A
CAS Number: 111682-13-4
Molecular Formula: C₂₀H₃₁ClN₄O₇
Molecular Weight: 474.94
Purity: ≥98% by TLC
Solubility:DMSO
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and mositure
SMILES: CC(C(=O)NC(C)C(=O)NC(=O)C1CCCN1C(C)C(=O)CCl)NC(=O)CCC(=O)OC
InChi: InChI=1S/C20H31ClN4O7/c1-11(22-16(27)7-8-17(28)32-4)18(29)23-12(2)19(30)24-20(31)14-6-5-9-25(14)13(3)15(26)10-21/h11-14H,5-10H2,1-4H3,(H,22,27)(H,23,29)(H,24,30,31)/t11-,12-,13-,14-/m0/s1
InChi Key: RHGXHACEVXSAHV-XUXIUFHCSA-N
PubChem CID: 5748191
MDL Number: MFCD00238296
USAGE: For Research Use Only! Not For Use in Humans. |