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17-DMAG hydrochloride
A Hsp90 inhibitor
Product Overview
Product Name: 17-DMAG hydrochloride
Alternate Name/Synonyms: 17-(Dimethylaminoethylamino)-17-demethoxygeldanamycin Hydrochloride; Alvespimycin
Description: A water-soluble analog of 17-AAG (Cat. No. 1774-1,5) that displays better stability and low in vivo toxicity similar to 17-AAG, but undergoes limited metabolism compared to 17-AAG. Binds specifically to heat shock protein90 (Hsp90) in a manner similar to geldanamycin.
Peptide Sequence: N/A
Appearance: Purple solid
Formulation: N/A
CAS Number: 467214-21-7
Molecular Formula: C₃₂H₄₈N₄O₈•HCl
Molecular Weight: 653.21
Purity: ≥98% by HPLC
Solubility:DMSO or H₂O ( 2 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCCN(C)C)C)OC)OC(=O)N)C)C)O)OC.Cl
InChi: InChI=1S/C32H48N4O8.ClH/c1-18-14-22-27(34-12-13-36(5)6)24(37)17-23(29(22)39)35-31(40)19(2)10-9-11-25(42-7)30(44-32(33)41)21(4)16-20(3)28(38)26(15-18)43-8;/h9-11,16-18,20,25-26,28,30,34,38H,12-15H2,1-8H3,(H2,33,41)(H,35,40);1H/b11-9-,19-10+,21-16+;/t18-,20+,25+,26+,28-,30+;/m1./s1
InChi Key: DFSYBWLNYPEFJK-IHLRWNDRSA-N
PubChem CID: 9852573
MDL Number: N/A
USAGE: For Research Use Only! Not For Use in Humans. |