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Stat3 Inhibitor I, S3I-201
A Stat3 Inhibitor
Product Overview
Product Name: Stat3 Inhibitor I, S3I-201
Alternate Name/Synonyms: 2-Hydroxy-4-[[[[4-methylphenyl)sulfonyl]oxy]acetyl]amino]-benzoic acid; NSC 74859; S3I-201
Description: Inhibits Stat3.Stat3 complex formation and Stat3-DNA binding activity in vitro (IC₅₀ = 86 ± 33 µM) and Stat3-dependent transcriptional activities. S3I-201 inhibits the expression of the Stat3-regulated genes encoding cyclin D1, Bcl-xL, and survivin and inhibits the growth of human breast tumors in vivo.
Peptide Sequence: N/A
Appearance: Off-white solid
Formulation: N/A
CAS Number: 501919-59-1
Molecular Formula: C₁₆H₁₅NO₇S
Molecular Weight: 365.36
Purity: ≥97% by HPLC
Solubility:DMSO (10 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: CC1=CC=C(C=C1)S(=O)(=O)OCC(=O)NC2=CC(=C(C=C2)C(=O)O)O
InChi: InChI=1S/C16H15NO7S/c1-10-2-5-12(6-3-10)25(22,23)24-9-15(19)17-11-4-7-13(16(20)21)14(18)8-11/h2-8,18H,9H2,1H3,(H,17,19)(H,20,21)
InChi Key: HWNUSGNZBAISFM-UHFFFAOYSA-N
PubChem CID: 252682
MDL Number: MFCD09907564
USAGE: For Research Use Only! Not For Use in Humans. |