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Aurora Kinase B Inhibitor (AZD1152-HQPA)
Product Overview
Product Name: Aurora Kinase B Inhibitor (AZD1152-HQPA)
Alternate Name/Synonyms: AZD1152-HQPA
Description: A potent and specific Aurora kinase B inhibitor. It is 1000-fold more selective for aurora kinase B than for aurora kinase A ( Ki values of 1300 nM and 0.36 nM for aurora kinase A and B, respectively). At concentrations as low as 0.01 µM, AZD 1152 produced a significant (p<0.05) decrease in the ability of NB4 cells to proliferate by 48 hours.
Peptide Sequence: N/A
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 722544-51-6
Molecular Formula: C₂₆H₃₀FN₇O₃
Molecular Weight: 507.56
Purity: ≥99% by HPLC
Solubility:DMSO
Storage Temp.: -20°C
Shipping Conditions: RT
Handling: Protect from light and moisture
SMILES: CCN(CCCOC1=CC2=C(C=C1)C(=NC=N2)NC3=NNC(=C3)CC(=O)NC4=CC(=CC=C4)F)CCO
InChi: InChI=1S/C26H30FN7O3/c1-2-34(10-11-35)9-4-12-37-21-7-8-22-23(16-21)28-17-29-26(22)31-24-14-20(32-33-24)15-25(36)30-19-6-3-5-18(27)13-19/h3,5-8,13-14,16-17,35H,2,4,9-12,15H2,1H3,(H,30,36)(H2,28,29,31,32,33)
InChi Key: QYZOGCMHVIGURT-UHFFFAOYSA-N
PubChem CID: 16007391
MDL Number: MFCD10687152
USAGE: For Research Use Only! Not For Use in Humans. |