|
Saracatinib (AZD0530)
Product Overview
Product Name: Saracatinib (AZD0530)
Alternate Name/Synonyms: AZD-0530
Description: AZD0530 is a dually active inhibitor of c-Src and Bcr-ABL, on bone resorption. AZD0530 inhibited tumor growth in a manner independent of dose and inhibited phosphorylation of focal adhesion kinase (FAK) and paxillin in a dose-dependent manner in a Calu-6 Xenograft model.
Peptide Sequence: N/A
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 379231-04-6
Molecular Formula: C₂₇H₃₂ClN₅O₅
Molecular Weight: 542.03
Purity: ≥99% by HPLC
Solubility:DMSO (~ 200 mg/ml) or EtOH (~ 200 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: RT
Handling: Protect from light and moisture
SMILES: CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6
InChi: InChI=1S/C27H32ClN5O5/c1-32-6-8-33(9-7-32)10-13-35-19-14-21-24(23(15-19)38-18-4-11-34-12-5-18)27(30-16-29-21)31-25-20(28)2-3-22-26(25)37-17-36-22/h2-3,14-16,18H,4-13,17H2,1H3,(H,29,30,31)
InChi Key: OUKYUETWWIPKQR-UHFFFAOYSA-N
PubChem CID: 10302451
MDL Number: MFCD09832698
USAGE: For Research Use Only! Not For Use in Humans. |