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PD184352
Description
A potent and selective inhibitor of MEK, a key component of the Mitogen activated protein kinase (MAPK) cascade. It has been found to induce apoptosis, has antiproliferative and antitumor activities.
Specifications
Cas No. 212631-79-3
Product ID P1200
Product Name PD184352
Formula Wt. 478.66
Solubility Soluble in DMSO
References Pohl, G., et al. Cancer Res. 65: 1994-2000 (2005) RR Mattingly et al. J. Pharmacol. Exp. Ther. 2006, 316, 456-465. D Liu et al. J. Clin. Endocrinol. & Meta. 2007, 92 (12), 4686-4695.
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