(R)-Bromoenol lactone-d7

产品编号：	10534-500 查看说明书
产品名称：	(R)-Bromoenol lactone-d7 .0 订购此产品
供应商：	Cayman
规格：	500 碌g
目录价：	2017.4
库存状态：	3周
CAS编号：
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相关信息：
(R)-Bromoenol lactone-d7 Exclusive Cayman Chemical Item Number 10534 Description (R)-Bromoenol lactone-d7 ((R)-BEL-d7) contains seven deuterium atoms at the 2, 3, 4, 5, 6, 7, and 8 positions. It is intended for use as an internal standard for the quantification of (R)-BEL by GC- or LC-mass spectrometry (MS). The phospholipases are an extensive family of lipid hydrolases that function in cell signaling, digestion, membrane remodeling, and as venom components.1↗ The calcium-independent phospholipase A2 (iPLA2) are a PLA2 subfamily closely associated with the release of arachidonic acid in response to physiologic stimuli. (R)-Bromoenol lactone ((R)-BEL) is an irreversible, chiral, mechanism-based inhibitor of iPLA2γ. Unlike (S)-BEL, (R)-BEL does not inhibit iPLA2β except at high doses of 20-30 µM.2↗ (R)-BEL inhibits human recombinant iPLA2γ with an IC50 of approximately 0.6 µM. Synonyms (R)-BEL-d7 Formal Name 6E-(bromoethylene)tetrahydro-3R-(1-naphthalenyl-2,3,4,5,6,7,8-d7)-2H-pyran-2-one Molecular Formula C16H6BrD7O2 Formula Weight 324.2 Formulation A solution in methyl acetate Purity ≥99% deuterated forms (d1-d7) λmax 280 nm Stability 1 year Storage -20°C Shipping Wet ice in continental US; may vary elsewhere SMILES [2H]C1=C([2H])C([2H])=C2C(C([2H])=C([2H])C([2H])=C2[C@]3([H])C(O/C(CC3)=C/Br)=O)=C1[2H].CC InCHI Code 1S/C16H13BrO2/c17-10-12-8-9-15(16(18)19-12)14-7-3-5-11-4-1-2-6-13(11)14/h1-7,10,15H,8-9H2/b12-10+/t15-/m1/s1/i1D,2D,3D,4D,5D,6D,7D InCHI Key BYUCSFWXCMTYOI-ROCJGVDXSA-N
保存条件：	-20°C
说明书地址：	点击查看详细

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