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D-myo-Inositol-1,2,4,5-tetraphosphate (sodium salt)
Cayman Chemical Item Number 10008451
Description
D-myo-Inositol-1,2,4,5-tetraphosphate (Ins(1,2,4,5)P4) is one of the many inositol phosphate (InsP) isomers that act as small, soluble second messengers in the transmission of cellular signals.1↗,2↗,3↗. Ins(1,2,4,5)P4 exhibits agonist activity at the Ins(1,4,5)P3 receptor expressed in CHO cells where it induces Ca2+ mobilization with an ED50 value of 0.22 µM, making it nearly equipotent to Ins(1,4,5)P3 (EC50 = 0.1 µM) in the same assay.4↗
Synonyms Ins(1,2,4,5)P4 (sodium salt)
1,2,4,5-IP4 (sodium salt)
Formal Name D-myo-Inositol-1,2,4,5-tetrakis(dihydrogen phosphate), tetrasodium salt
Molecular Formula C6H12O18P4· 4Na
Formula Weight 588.0
Formulation A lyophilized powder
Purity ≥98%
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES O[C@@H]1[C@@H](OP([O-])(O)=O)[C@H](OP([O-])(O)=O)[C@@H](O)[C@@H](OP([O-])(O)=O)[C@H]1OP([O-])(O)=O.[Na+].[Na+].[Na+].[Na+]
InCHI Code 1S/C6H16O18P4.4Na/c7-1-3(21-25(9,10)11)5(23-27(15,16)17)2(8)6(24-28(18,19)20)4(1)22-26(12,13)14;;;;/h1-8H,(H2,9,10,11)(H2,12,13,14)(H2,15,16,17)(H2,18,19,20);;;;/q;4*+1/p-4/t1-,2-,3?,4?,5?,6?;;;;
InCHI Key GPEDWSWFXATPAL-ZGXJPNOWSA-J |