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D-myo-Inositol-1,2,5,6-tetraphosphate (sodium salt)
Cayman Chemical Item Number 10008444
Description
D-myo-Inositol-1,2,5,6-tetraphosphate (Ins(1,2,5,6)P4) is one of the many inositol phosphate isomers that act as small, soluble second messengers in the transmission of cellular signals.1↗,2↗,3↗. Ins(1,2,5,6)P4 binds to the murine Grp-1 PH domain with a Kd(apparent) of 0.18 µM, which is about 6.7-fold higher than for Ins(1,3,4,5)P4.4↗ It binds to rat heart membranes and significantly decreases heart rate in a pithed rat model.5↗
Synonyms Ins(1,2,5,6)P4 (sodium salt) 1,2,5,6-IP4 (sodium salt)
Formal Name D-myo-inositol-1,2,5,6-tetra(dihydrogen phosphate), tetrasodium salt
Molecular Formula C6H12O18P4· 4Na
Formula Weight 588.0
Formulation A lyophilized powder
Purity ≥98%
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES O[C@@H]1[C@@H](O)[C@@H](O[P+]([O-])(O)=O)[C@@H](OP([O-])(O)=O)[C@H](OP([O])(O)=O)[C@H]1OP([O-])([OH+])=O.[Na+].[Na].[Na].[Na]
InCHI Code 1S/C6H16O18P4.4Na/c7-1-2(8)4(22-26(12,13)14)6(24-28(18,19)20)5(23-27(15,16)17)3(1)21-25(9,10)11;;;;/h1-8H,(H2,9,10,11)(H2,12,13,14)(H2,15,16,17)(H2,18,19,20);;;;/q;4*+1/p-4/t1-,2-,3?,4?,5?,6?;;;;/m1..../s1
InCHI Key DZJJWPAQUIBBLR-SEPOYWDNSA-J |