Pam3CSK4 Biotin Biotinylated synthetic triacylated lipoprotein Pam3CSK4 is a synthetic triacylated lipopeptide (LP) that mimics the acylated amino terminus of bacterial LPs. Pam3CSK4 is a potent activator of the proinflammatory transcription factor NF-κB. Activation is mediated by the interaction between TLR2 and TLR1 which recognize LPs with three fatty acids, a structural characteristic of bacterial LPs. Specificity: TLR 1/2 agonist Working concentration: 10 - 300 ng/ml Molecular formula: C103H192N14O17S2, 2 TFA Molecular weight: 1962.9 Endotoxin level: <0.001 EU/μg
