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Pam2CSK4 Biotin
Biotinylated synthetic diacylated lipoprotein
Pam2CSK4 Biotin is a biotinylated synthetic diacylated lipopeptide (LP). According to the current model, diacylated LPs induce signaling through TLR2/6. However, it was also reported that Pam2CSK4 induces signaling in a TLR6-independent manner. This finding suggests that both the lipid and peptide part of lipoproteins take part in the specificity of recognition by TLR2 heterodimers.
Pam2CSK4 Biotin can be used for various applications, such as evaluating cellular uptake and localization of Pam2CSK4 using a biotin detection system and light microscopy.
Specificity: TLR2(6) agonist
Working concentration: 1 - 100 ng/ml
Molecular formula: C87H162N14O16S2
Molecular weight: 1952.6
Endotoxin level: <0.001 EU/μg |