Alum Crystals NLRP3 Inflammasome Inducer Alum crystals has been demonstrated to activate caspase-1 and trigger IL-1β and IL-18 secretion [1]. The alum-induced release of IL-1β in macrophages is dependent on NALP3 and ASC, indicating that alum triggers inflammation through activation of the NALP3 inflammasome [2]. Working concentration: 10 - 200 µg/ml CAS number: 7784-24-9 Molecular weight: 474.39 Purity: ≥98.0% Endotoxin level: <0.125 EU/mg Solubility: Clear to slightly hazy colorless solution at 0.5 M in H2O
