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Ficoll PM70
Application: Specifically intended for use in perfusion media for laboratory studies on dextran-sensitive animals.
Endotoxin Activity Max.: 0.12 EU/mg
Storage Conditions: 4 - 30°C
Stability: Stable in alkaline and neutral solutions, but are rapidly hydrolyzed in solution at pH 3, especially at elevated temperature
Physical Stat:e Solid
Physical Form: Spray-dried powder
Molecular Weight [Mr] Max.: ~ 8 x 104
Molecular Weight [Mr] Min.: ~ 6 x 104
Reactivity and Stability: The reactivity and stability of Ficoll PM70 are determined by its hydroxyl groups and the glycosidic bonds in the sucrose residues. It is stable in alkaline and neutral solutions. At pH values lower than 3, it is rapidly hydrolyzed, especially at elevated temperatures. In neutral solutions, however, Ficoll PM 400 can be sterilized by autoclaving at 110°C for 30 min without degradation. Strong oxidizing and reducing agents should be avoided.
Stokes Radius: ~ 5.1 nm
Color: White
Specific Rotation [alpha]20: 50°-65°
Intrinsic Viscosity: ~ 10 ml/g
Solubility: It is delivered as a spray-dried powder and is therefore readily soluble in aqueous media when it is added slowly with concomitant stirring. Any lumps formed during this procedure will dissolve fairly quickly. Concentrations up to 50% (w/v) can easily be attained |