|
Rho Kinase Inhibitor IV
(S)-(+)-2-Methyl-4-glycyl-1-(4-methylisoquinolinyl-5-sulfonyl)homopiperazine, 2HCl, H-1152, Glycyl
A cell-permeable, reversible, and ATP-comptetive glycyl analog of Rho-Kinase Inhibitor (Cat. No. 555550) that inhibits ROCK with an improved selectivity (IC50 = 11.8 nM, > 10 µM, > 10 µM, 3.26 µM, 2.35 µM, and 2.57 µM for ROCKII, PKA, PKC, PKG, Aurora A, and CaMKII, respectively).
产品信息
Form Pale yellow solid
Primary Target ROCK II
Primary Target IC50 11.8 nM
Secondary target IC50 = 10 µM, >10 µM, 3.26 µM, 2.35 µM, and 2.57 µM for PKA, PKC, PKG, Aurora A, and CaMKII, respectively
Molar mass 467.4
Protect from Light 是的
Hygrocopic 是的
Packaged under inert gas 是的
Purity ≥98% by HPLC
Solubility DMSO or H2O
Chemical formula C18H24N4O3S • 2HCl • H2O
商店和运输信息
Storage +2°C to +8°C
Ship Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Harmful |