PTP Inhibitor IV
bis(4-Trifluoromethylsulfonamidophenyl)-1,4-diisopropylbenzene, Protein Tyrosine Phosphatase Inhibitor IV
An uncharged, 1,4-di-substituted, phenyl-linked bis-trifluoromethylsulfonamido (TFMS) phosphate mimetic that acts as a potent, reversible, competitive, and active-site directed inhibitor of protein tyrosine phosphatases (PTP; IC50 = 1.8, 2.5, 8.4, 13, 20, 6.4, and 6.7 µM for SHP-2, PTP1B, PTP-ε, PTP-Meg-2, PTP-σ, PTP-β, and PTP-µ, respectively).
产品信息
Form White to off-white solid
Primary Target SHP-2
Primary Target IC50 1.8 µM
Secondary target IC50 = 2.5, 8.4, 13, 20, 6.4, and 6.7 µM for PTP1B, PTP-ε, PTP-Meg-2, PTP-σ, PTP-beta;, and PTP-µ, respectively
Molar mass 608.6
Protect from Light 是的
Packaged under inert gas 是的
Reversible 是的
Purity ≥95% by HPLC
Solubility DMSO
Chemical formula C26H26F6N2O4S2
CAS number 329317-98-8
商店和运输信息
Storage +2°C to +8°C
Ship Ambient Temperature Only
Standard Handling |