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PTP Inhibitor III
α-Bromo-4-(carboxymethoxy)acetophenone, 4-(Carboxymethoxy)phenacyl Br, Protein Tyrosine Phosphatase Inhibitor III, SHP1 Inhibitor III, PTP-MEG2/PTPN9 Inhibitor, PTP-β Inhibitor, PTP-δ Inhibitor, PTP-ε Inhibitor, PTP-µ Inhibitor, PTP1B Inhibitor III, SHP2 Inhibitor II
A potent, cell-permeable, and covalent protein tyrosine phosphatase (PTP) inhibitor. Binds to SHP-1 (ΔSH2), the catalytic domain of the SH2 domain-containing phosphatase SHP-1, with lower affinity than PTP Inhibitor I (Cat. No. 540200) (Ki = 193 µM versus Ki = 43 µM) but with a higher kinact (1.8 min-1 versus 0.4 min-1). The inhibition can be reversed by irradiation of the inactivated PTP at 350 nm.
产品信息
Form White solid
Primary Target PTP
Primary Target IC50 193 µM
Molar mass 273.1
Protect from Light 是的
Packaged under inert gas 是的
Cell permeable 是的
Purity ≥90% by HPLC
Solubility DMSO
Chemical formula C10H9BrO4
CAS number 29936-81-0
商店和运输信息
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage ≤ -70°C
Ship Blue Ice Only
Corrosive |