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PI 3-Kβ Inhibitor VI, TGX-221
(±)-7-Methyl-2-(morpholin-4-yl)-9-(1-phenylaminoethyl)-pyrido[1,2-a]-pyrimidin-4-one, PI 3-K Inhibitor VI
A cell-permeable morpholino-pyrimidinone compound that acts as a reversible, ATP-competitive, selective, and highly potent inhibitor of PI 3-Kβ (IC50 = 0.005, 0.1, 5, and ≥3.5 µM for -β, -δ, -α and -γ isoforms, respectively) with little activity against a panel of 15 commonly studied protein kinases even at concentrations as high as 10.0 µM. An excellent tool for studying p110β-dependent responses both in cells in vitro and in animals in vivo.
产品信息
Form White solid
Molar mass 364.4
Protect from Light 是的
Packaged under inert gas 是的
Purity ≥97% by HPLC
Solubility DMSO or EtOH
Chemical formula C21H24N4O2
CAS number 663619-89-4
商店和运输信息
Storage +2°C to +8°C
Ship Ambient Temperature Only
Standard Handling |