|
PD 169316
4-(4-Fluorophenyl)-2-(4-nitrophenyl)-5-(4-pyridyl)-1H-imidazole
A potent, cell-permeable, reversible, competitive, and selective p38 MAP kinase inhibitor (IC50 = 89 nM). Inhibition of p38 MAP kinase by PD 169316 blocks apoptosis induced by trophic factor withdrawal in non-neuronal and neuronal cell lines.
产品信息
Form Orange-yellow solid
Primary Target p38 MAP kinase
Primary Target IC50 89 nM
Molar mass 360.3
Protect from Light 是的
Cell permeable 是的
Purity ≥98% by HPLC
Solubility DMSO
Chemical formula C20H13FN4O2
CAS number 152121-53-4
商店和运输信息
Storage -20°C
Ship Ambient Temperature Only
Standard Handling |