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Nogo-66 (1-40) Antagonist Peptide, Synthetic
Nogo Extracellular Peptide, 1-40, NEP1-40, Ac-RIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNS-NH2
An end-protected 40-mer peptide derived from the N-terminal fragment of the Nogo-66 domain that acts as a selective, competitive, high affinity antagonist of Nogo-66 receptor (NgR). Although NgR serves as the common receptor for both Nogo-66 and MAG (myelin-associated glycoprotein), NEP1-40 blocks only the inhibition of neurite outgrowth induced by Nogo-66, but not that by MAG. Promotes axonal regeneration after spinal cord injury in rats.
产品信息
Peptide Sequence Ac-Arg-Ile-Tyr-Lys-Gly-Val-Ile-Gln-Ala-Ile-Gln-Lys-Ser-Asp-Glu-Gly-His-Pro-Phe-Arg-Ala-Tyr-Leu-Glu-Ser-Glu-Val-Ala-Ile-Ser-Glu-Glu-Leu-Val-Gln-Lys-Tyr-Ser-Asn-Ser-NH2
Form White solid
Formulation Supplied as a trifluoroacetate salt.
Molar mass 4625.2
Protect from Light 是的
Hygrocopic 是的
Packaged under inert gas 是的
Purity ≥95% by HPLC
Solubility DMSO
Chemical formula C206H324N56O65
商店和运输信息
Storage -20°C
Ship Blue Ice Only
Standard Handling |