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Nociceptin
Endogenous ligand for the opioid-like G-protein coupled receptor, ORL1 (Opioid Receptor-Like 1). Has no significant activity on the µ, δ, or κ opioid receptors; however, nanomolar concentrations of nociceptin inhibit forskolin-stimulated adenylyl cyclase activity in cells transfected with the G-protein coupled receptor LC132, which is similar in sequence to the opioid receptor. Also reported to cause hypertension and bradycardia in mice.
产品信息
Peptide Sequence H-Phe-Gly-Gly-Phe-Thr-Gly-Ala-Arg-Lys-Ser-Ala-Arg-Lys-Leu-Ala-Asn-Gln-OH
Form White lyophilized solid
Formulation Supplied as a trifluoroacetate salt.
Molar mass 1809.1
Hygrocopic 是的
Purity ≥98% by HPLC
Solubility H2O
Chemical formula C79H129N27O22
CAS number 170713-75-4
商店和运输信息
Storage -20°C
Ship Ambient Temperature Only
Standard Handling |