|
产品说明
Contains the nuclear localization sequence (NLS) of the transcription factor NF-κB p50 linked to the hydrophobic region (h-region) of the signal peptide of Kaposi fibroblast growth factor (K-FGF). The N-terminal K-FGF h-region confers cell-permeability, while the NLS (360-369) inhibits translocation of the NF-κB active complex into the nucleus. In murine endothelial LE-II cells induced by LPS, NF-κB nuclear translocation is maximally inhibited at 18 µM.
产品信息
Form Lyophilized
Formulation Supplied as a trifluoroacetate salt.
Primary Target translocation of the NF-κB active complex into the nucleus
Hygrocopic 是的
Cell permeable 是的
Purity ≥97% by HPLC
Sold on the basis of peptide content 是的
Chemical formula C129H230N36O29S
Declaration Sold under license of U.S. Patents 5,807,746 and 6,043,339 for research use only. Licenses for commercial manufacture, commercial use, diagnostics, or therapeutics may be obtained by contacting Vanderbilt University, Nashville, Tennessee.
Storage -20°C
Ship Ambient Temperature Only
Standard Handling |