正品|NF-KB ACTIVATION INHIBITOR VI, BOT-64

产品说明
A cell-permeable benzoxathiole compound that acts as an IKK-2 inhibitor, presumably by targeting the Ser177 and/or Ser181 residues in the kinase's activation loop domain. Shown to inhibit LPS-induced NF-κB activation and nitrite production (IC50 = 1.0 & 0.7 µM, respectively) in RAW 264.7 cells in vitro and effectively prevent LPS-induced septic death in mice (70% survival rate with 30 mg/kg BOT-64, i.p.) in vivo.
产品信息 
Form  Off-white solid 
Protect from Light  是的 
Packaged under inert gas  是的 
Purity  ≥95% by HPLC 
Chemical formula  C15H15NO2S 
CAS number  113760-29-5 
Storage  -20°C 
Ship  Shipped with Blue Ice or with Dry Ice
Standard Handling