产品说明 A cell-permeable salicylamide compound that acts as an IKK-2 inhibitor by selectively blocking IκBα phosphorylation (IC50 ~ 250 nM) and thereby prevents the induction of NF-κB p65 nuclear translocation. Shown to offer cardioprotection by reducing IL-1β and MCP-1 production (IC50 < 1 µM) in cardiomyocytes, and ameliorate insulin resistance in KKAy mice by regulating adiponectin release. 产品信息 Form White solid Primary Target IKK-2 Primary Target IC50 250 nM Secondary target IL-1β and MCP-1 production (IC50 < 1 µM) Protect from Light 是的 Packaged under inert gas 是的 Cell permeable 是的 Purity ≥95% by HPLC Chemical formula C15H8ClF6NO2 CAS number 978-62-1 Storage +2°C to +8°C Ship Ambient Temperature Only Standard Handling