GENISTEIN, SOYBEAN|正品进口

产品说明
A cell-permeable, reversible, substrate competitive inhibitor of protein tyrosine kinases, including autophosphorylation of epidermal growth factor receptor kinase (IC50 = 2.6 µM). The inhibition is competitive with respect to ATP and non-competitive with respect to the phosphate acceptor. Has only a trivial effect on the activity of PKA and PKC (IC50 > 350 µM). Inhibits tumor cell proliferation and induces tumor cell differentiation. Produces cell cycle arrest and apoptosis in Jurkat T-leukemia cells. However, it prevents anti-CD3 monoclonal antibody-induced thymic apoptosis. Also inhibits topoisomerase II activity in vitro.
产品信息 
Form  White solid 
Primary Target  EGFR kinase 
Primary Target IC50  2.6 µM 
Protect from Light  是的 
Purity  ≥95% by HPLC 
Chemical formula  C15H10O5 
RTECS  NR2392000 
CAS number  446-72-0 
Merck USA index  14, 4391 
Storage  -20°C 
Ship  Ambient Temperature Only
Standard Handling